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Title:
炭水化物、脂質、またはアミノ酸キャリアを含むγ-ヒドロキシブチレート組成物
Document Type and Number:
Japanese Patent JP2004509900
Kind Code:
A
Abstract:
The present invention provides compositions comprising at least one GHB moiety bonded to at least one physiologically compatible carrier molecule. The compositions can enhance the uptake of the drug, deliver effective therapeutic doses in a time-delayed fashion, or can target specific organs.

Inventors:
Mamelac, Mortimer
Houghton, William Sea.
Rare Dunn, Dayton Tea.
Miller, Brian El.
Application Number:
JP2002529123A
Publication Date:
April 02, 2004
Filing Date:
September 21, 2001
Export Citation:
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Assignee:
Orphan Medical, Incorporated
International Classes:
A61K31/22; A61K31/223; A61K31/225; A61K31/70; A61K31/7024; A61K31/716; A61K47/48; A61P1/00; A61P1/04; A61P3/10; A61P5/00; A61P5/06; A61P9/00; A61P9/10; A61P23/00; A61P25/00; A61P25/04; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/36; A61P29/00; A61P37/06; A61P39/00; A61P39/06; A61P43/00; C07C69/003; C07C69/34; C07C69/52; C07C69/63; C07C69/67; C07H13/06; C07C69/675; C07C229/22; C07C229/24; C07C229/36; C07C233/47; C07C233/49; C07H13/04; C07H15/04; C07J21/00; C08B13/00; C08B31/00; (IPC1-7): C07H13/06; A61K31/22; A61K31/223; A61K31/7024; A61K47/48; A61P1/00; A61P1/04; A61P3/10; A61P5/00; A61P5/06; A61P9/00; A61P9/10; A61P23/00; A61P25/00; A61P25/04; A61P25/16; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P25/32; A61P25/36; A61P29/00; A61P37/06; A61P39/00; A61P39/06; A61P43/00; C07C69/003; C07C69/63; C07C69/675; C07J21/00; C08B13/00; C08B31/00
Domestic Patent References:
JPH0776522A1995-03-20
JPH03173854A1991-07-29
JPH09505579A1997-06-03
JPH09505581A1997-06-03
JPH09505580A1997-06-03
JPS4961155A1974-06-13
JPH06508610A1994-09-29
JPH0733654A1995-02-03
JP2001513552A2001-09-04
Foreign References:
WO2001019361A22001-03-22
WO1998041201A11998-09-24
DE2702687A11978-07-27
Other References:
JPN6011064681; Journal of the American Chemical Society Vol.111, No.4, 1989, p.1392-1396
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita