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Title:
HYDROXYSTEROID DEHYDROGENASE INHIBITOR
Document Type and Number:
Japanese Patent JP2012255004
Kind Code:
A
Abstract:

To provide novel hydroxysteroid dehydrogenase inhibiting compounds.

There are provided the following compounds, and further pharmaceutical compositions containing the same for type-2 diabetes, osteoporosis, hypertension, ocular disorders, cognitive disorders, the metabolic syndrome and other metabolic disorders.


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Inventors:
AERTGEERTS KATHLEEN
BRENNAN NANCY K
CAO SHELDON X
CHANG EDCON
KIRYANOV ANDRE A
LIU YAN
Application Number:
JP2012173398A
Publication Date:
December 27, 2012
Filing Date:
August 03, 2012
Export Citation:
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Assignee:
TAKEDA CALIFORNIA INC
International Classes:
C07D207/14; A61K31/40; A61K31/4025; A61K31/404; A61K31/407; A61K31/4355; A61K31/44; A61K31/445; A61K31/454; A61K31/4545; A61K31/4709; A61K31/472; A61K31/495; A61K31/496; A61K31/498; A61K31/4985; A61K31/506; A61K31/5377; A61K31/538; A61P3/00; A61P3/10; A61P9/12; A61P19/10; A61P25/28; A61P27/02; A61P43/00; C07D209/08; C07D211/10; C07D211/18; C07D211/22; C07D211/34; C07D211/58; C07D211/70; C07D213/38; C07D213/42; C07D213/71; C07D215/36; C07D217/02; C07D217/08; C07D231/18; C07D231/56; C07D233/84; C07D239/42; C07D241/04; C07D241/18; C07D241/50; C07D261/10; C07D265/36; C07D271/12; C07D277/20; C07D277/42; C07D277/62; C07D285/14; C07D295/22; C07D307/82; C07D319/18; C07D401/04; C07D401/12; C07D401/14; C07D403/12; C07D409/12; C07D413/04; C07D471/04; C07D487/04; C07D487/08; C07D491/113; C07D513/04
Domestic Patent References:
JPH02184673A1990-07-19
JP5140577B22013-02-06
JPS57156463A1982-09-27
JPS54104931A1979-08-17
JPS60109574A1985-06-15
JPS63211271A1988-09-02
JP2002255937A2002-09-11
JP2002506859A2002-03-05
JP2004533435A2004-11-04
Foreign References:
WO2003042174A12003-05-22
WO2004111014A12004-12-23
WO2004033427A12004-04-22
WO2003037890A22003-05-08
Other References:
PHOSPHORUS, SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 179(6), JPN6011054157, 2004, pages 1085 - 1093, ISSN: 0002729173
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Kenji Yamamoto
Murata Miyuki
Junzo Koike
Hirofumi Toma



 
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