Title:
IL-15アンタゴニスト
Document Type and Number:
Japanese Patent JP2006518583
Kind Code:
A
Abstract:
The invention relates to fusion proteins consisting of a wild-type IL-15 and a IgG-Fc fragment, apart from a mouse IgG2b fragment, nucleic acids encoding said proteins, vectors, modified cells, and also to the use thereof for preparing drugs which are used, for example for preventing and/or curing disorders resulting from a transplantation and/or autoimmune diseases.
Inventors:
Dreyer, Ingeborg
Mol, thomas
Mol, thomas
Application Number:
JP2004543889A
Publication Date:
August 17, 2006
Filing Date:
October 13, 2003
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C12N15/09; A01K67/027; A61K35/48; A61K35/76; A61K38/00; A61K48/00; A61P37/06; A61P41/00; A61P43/00; C07K14/54; C07K16/00; C07K19/00; C12N5/10; C12N15/62; C12P21/02
Domestic Patent References:
| JPH11501506A | 1999-02-09 |
Other References:
TRANSPLANT.PROC.,VOL.30(1998)P.4031-4036, JPN6009038458, ISSN: 0001381872
EUR.J.IMMUNOL.,VOL.28(1998)P.3312-3320, JPN6009038462, ISSN: 0001381873
J.IMMUNOL.,VOL.167(2001)P.3478-3485, JPN6009038463, ISSN: 0001381874
EUR.J.IMMUNOL.,VOL.28(1998)P.3312-3320, JPN6009038462, ISSN: 0001381873
J.IMMUNOL.,VOL.167(2001)P.3478-3485, JPN6009038463, ISSN: 0001381874
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita