Title:
【発明の名称】15,15-ジアルキル置換されたエストラジオール誘導体
Document Type and Number:
Japanese Patent JPH09500891
Kind Code:
A
Abstract:
New 15,15-dialkyl-substituted derivatives of the estradiol of general formula I (I) in which R1 and R2, independently of one another, are each a hydrogen atom or a straight-chain alkanoyl group with 1 to 10 carbon atoms, a branched-chain alkanoyl group with 3-10 carbon atoms, an alkanoyl group of 3-10 carbon atoms containing a cycloaliphatic structure of 3-6 carbon ring atoms or a benzoyl group, and R3 and R4, independently of one another, are each a straight-chain alkyl group with 1 to 10 carbon atoms or a branched-chain alkyl group with 3 to 10 carbon atoms, are described, a process for their production and initial products for this process. The new compounds have-also after oral administration-high estrogenic effectiveness and are suitable for the production of pharmaceutical agents.
Inventors:
Bull, James Ronald
Fritzheimer, Karl-Heinrich
Heggele-Hartung, Christa
Fritzheimer, Karl-Heinrich
Heggele-Hartung, Christa
Application Number:
JP50558195A
Publication Date:
January 28, 1997
Filing Date:
August 01, 1994
Export Citation:
Assignee:
Schering Actien Gezershaft
International Classes:
A61P5/00; C07J1/00; A61K31/565; (IPC1-7): C07J1/00; A61K31/565
Attorney, Agent or Firm:
Toshio Yano (3 outside)