Title:
【発明の名称】CTFレセプターアンタゴニストとして有用なアミノ置換チアジアゾール、ピリミジン、トリアジン、またはトリアゾール
Document Type and Number:
Japanese Patent JPH11507358
Kind Code:
A
Abstract:
CRF receptor antagonists are disclosed. Such receptor antagonists are thiadiazole-, pyrimidine-, triazine-, and triazole-containing compounds substituted with both a C3-C14 monocyclic or fused, homoaryl or heteroaryl group and a substituted amine group. The CFR receptor antagonists have utility in the treatment of a variety of disorders, including disorders associated with the hypersecretion of CRF.
Inventors:
McKersey, James Earl.
Si, Yun Feng
Witton, Jeffrey Pee.
Web, Thomas Earl.
Chain
Ranfal, John Wye.
Grigori Adis, Dimitri E.
Dagnino, raymond junior
Fan, Charles Kew.
Ryu, Chen Yu
Si, Yun Feng
Witton, Jeffrey Pee.
Web, Thomas Earl.
Chain
Ranfal, John Wye.
Grigori Adis, Dimitri E.
Dagnino, raymond junior
Fan, Charles Kew.
Ryu, Chen Yu
Application Number:
JP50191297A
Publication Date:
June 29, 1999
Filing Date:
June 06, 1996
Export Citation:
Assignee:
Neurocline Biosciences, Inc.
International Classes:
A61K31/41; A61K31/433; A61K31/505; A61K31/53; A61P1/12; A61P3/04; A61P5/38; A61P9/00; A61P11/00; A61P25/08; A61P25/18; A61P25/20; A61P25/30; A61P29/00; A61P37/00; A61P43/00; C07D239/42; C07D239/46; C07D239/48; C07D249/14; C07D251/14; C07D251/16; C07D251/18; C07D251/22; C07D285/08; C07D491/052; (IPC1-7): C07D251/14; A61K31/41; A61K31/505; A61K31/53; C07D239/42; C07D249/14; C07D285/08; C07D491/052
Attorney, Agent or Firm:
Shusaku Yamamoto