Title:
【発明の名称】酸化窒素合成酵素インヒビターとして有用なアミノテトラゾール誘導体
Document Type and Number:
Japanese Patent JP3278165
Kind Code:
B2
Abstract:
Compounds having formula (I) and pharmaceutically acceptable salts thereof, wherein B is NR<5>R<11>, wherein R<5> is selected from the group consisting of hydrogen, lower alkyl, lower alkenyl, lower alkynyl and aryl, and R<11> is selected from a 3 to 8 member heterocyclyl radical in which at least one member of the ring is carbon and in which 1 to about 4 members are heteroatoms independently selected from oxygen, nitrogen and sulfur and said heterocyclyl radical may be optionally substituted, useful as nitric oxide synthase inhibitors.
Inventors:
Harinan, E. Ann
Hansen, Donald W., Giunia
Tosim Barov, Sofya
Hansen, Donald W., Giunia
Tosim Barov, Sofya
Application Number:
JP51609696A
Publication Date:
April 30, 2002
Filing Date:
November 08, 1995
Export Citation:
Assignee:
G.D.Searle & Company
International Classes:
C12N9/99; A61K31/41; A61K31/415; A61K31/4168; A61K31/425; A61K31/426; A61K31/505; A61P9/00; A61P43/00; C07C257/14; C07D231/40; C07D233/88; C07D239/22; C07D239/42; C07D249/14; C07D257/06; C07D277/18; C07D277/20; C07D277/46; C07D277/50; (IPC1-7): C07D231/40; A61K31/41; A61K31/415; A61K31/425; A61K31/505; A61P43/00; C07D233/88; C07D239/42; C07D249/14; C07D257/06; C07D277/50; C12N9/99
Domestic Patent References:
| JP4270255A | ||||
| JP5500659A | ||||
| JP6506220A |
Other References:
【文献】国際公開93/13055(WO,A1)
Attorney, Agent or Firm:
Akira Asamura (3 outside)
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