Title:
【発明の名称】特異的なオリゴ糖-ニューレグリン相互作用のためのアナログおよびその使用
Document Type and Number:
Japanese Patent JP2000510879
Kind Code:
A
Abstract:
The present invention provides methods for modulating the interaction between neuregulins and neuregulin-specific glycosaminoglycan sequences. The invention identifies compounds that have the ability to mimic a specific neuregulin-glycosaminoglycan sequence interaction and provides methods for their selection and use as therapeutic agents.
More Like This:
Inventors:
Rache, James
Sudhalter, Judith
Mahan Sappa, Nagesh Kay.
Marchioni, Mark A.
Jacobson, Alan Earl.
Sudhalter, Judith
Mahan Sappa, Nagesh Kay.
Marchioni, Mark A.
Jacobson, Alan Earl.
Application Number:
JP51136697A
Publication Date:
August 22, 2000
Filing Date:
September 04, 1996
Export Citation:
Assignee:
Cambridge Neuroscience, Inc.
Rache, James
Sudhalter, Judith
Mahan Sappa, Nagesh Kay.
Marchioni, Mark A.
Jacobson, Alan Earl.
Proscure, Inc.
Rache, James
Sudhalter, Judith
Mahan Sappa, Nagesh Kay.
Marchioni, Mark A.
Jacobson, Alan Earl.
Proscure, Inc.
International Classes:
C07D295/12; A61K31/00; A61K31/275; A61K31/35; A61K31/351; A61K31/40; A61K31/403; A61K31/404; A61K31/4045; A61K31/44; A61K31/4406; A61K31/4427; A61K31/443; A61K31/535; A61K31/5375; A61K31/715; A61K31/726; A61K31/727; A61K38/00; A61K39/395; A61K45/00; A61K49/14; A61P9/00; A61P9/10; A61P35/00; A61P43/00; C07B61/00; C07C237/22; C07C309/17; C07C309/57; C07D209/12; C07D209/16; C07D213/82; C07D215/00; C07D233/00; C07D309/08; C07D315/00; C07D401/12; C07D405/12; C07D407/12; C08B37/08; G01N33/15; G01N33/50; G01N33/566; (IPC1-7): C08B37/08; A61K31/275; A61K31/351; A61K31/4045; A61K31/4406; A61K31/5375; A61K31/726; A61K31/727; A61K38/00; A61K39/395; A61K45/00; A61P9/10; A61P35/00; A61P43/00; C07C237/22; C07C309/17; C07C309/57; C07D209/12; C07D209/16; C07D213/82; C07D215/00; C07D233/00; C07D295/12; C07D309/08; C07D315/00; C07D401/12; C07D405/12; C07D407/12; G01N33/15; G01N33/50; G01N33/566
Attorney, Agent or Firm:
Shusaku Yamamoto