Title:
【発明の名称】抗コレシストキニン活性を有するアスパラギン酸及びグルタミン酸誘導体
Document Type and Number:
Japanese Patent JPH05508646
Kind Code:
A
Abstract:
PCT No. PCT/GB91/01111 Sec. 371 Date Jan. 12, 1993 Sec. 102(e) Date Jan. 12, 1993 PCT Filed Jul. 8, 1991 PCT Pub. No. WO92/00958 PCT Pub. Date Jan. 23, 1992.Arylsulfonamide derivatives of alpha -amino dicarboxylic acids such as aspartic acid and glutamic acid posses anti-cholecystokinin activity. They are useful in the treatment of cholecystokinin-related disorders such as anorexia nervosa, pancreatic inflammation, biliary tract disease, Zollinger-Ellison syndrome and various psychiatric disorders, as well as in the potentiation of opiate analgesia, and in the treatment of certain cancers.
Inventors:
Broughton, Howard Burff
Karin Jean, Sir Kiss Barrett
Lowe, Caroline Minri Rachel
McDonald's, Earin Meir
Hull, Robert Antony David
Shanley, Nigel Paul
Karin Jean, Sir Kiss Barrett
Lowe, Caroline Minri Rachel
McDonald's, Earin Meir
Hull, Robert Antony David
Shanley, Nigel Paul
Application Number:
JP51203091A
Publication Date:
December 02, 1993
Filing Date:
July 08, 1991
Export Citation:
Assignee:
James Black Foundation Limited
International Classes:
A61K31/195; A61K31/34; A61K31/341; A61K31/47; A61K31/472; A61P1/00; A61P43/00; C07C303/38; C07C311/06; C07C311/13; C07C311/14; C07C311/19; C07C311/29; C07D217/06; C07D255/02; C07D307/60; C07D307/66; (IPC1-7): C07C311/13; A61K31/195; A61K31/34; A61K31/47; C07C303/38; C07C311/14; C07C311/19; C07D217/06; C07D255/02; C07D307/60
Attorney, Agent or Firm:
Hiroaki Tazawa (2 outside)