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Patent Searching and Data


Title:
PURIFICATION OF NUCLEOSIDE DERIVATIVE
Document Type and Number:
Japanese Patent JPH0641129
Kind Code:
A
Abstract:

PURPOSE: To separate and purify the derivative useful as an anti-AIDS medicine or antiviral medicine from a crude 2',3'-dideoxynucleoside derivative accompanied by nucleic acid-related substances as impurities in a high purity and a high recovery rate.

CONSTITUTION: The 2',3'-dideoxynucleoside derivative is (a) extracted with an organic solvent and/or (b) crystallized from the 12 or higher pH basic aqueous solution of the crude 2',3'-dideoxynucleoside derivative.


Inventors:
HONDA YUTAKA
SHIRAGAMI HIROSHI
YUGAWA TOSHIHIDE
TAKAHASHI SATOJI
Application Number:
JP19996492A
Publication Date:
February 15, 1994
Filing Date:
July 27, 1992
Export Citation:
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Assignee:
AJINOMOTO KK
International Classes:
C07D405/04; C07B63/00; C07D473/18; C07D473/30; C07D473/34; (IPC1-7): C07D473/34; C07B63/00; C07D405/04; C07D473/18; C07D473/30
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)