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Title:
【発明の名称】システインプロテアーゼのICE/ced-3系の置換アシルジペプチジル抑制剤
Document Type and Number:
Japanese Patent JP2002527504
Kind Code:
A
Abstract:
This invention is directed to novel (substituted)acyl dipeptidyl ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.

Inventors:
Kara New Ski, Donald S.
Kalish, Vincent Jay.
Robinson, Edward Dee.
Ullman, Brett Earl.
Application Number:
JP2000577149A
Publication Date:
August 27, 2002
Filing Date:
October 22, 1999
Export Citation:
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Assignee:
Aiden Pharmaceuticals, Inc.
International Classes:
A61K31/197; A61K31/222; A61K31/225; A61K31/343; A61K31/351; A61K31/352; A61K31/37; A61K31/381; A61K31/401; A61K31/4035; A61K31/404; A61K31/41; A61K31/415; A61K31/4164; A61K31/4184; A61K31/4196; A61K31/42; A61K31/423; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/4402; A61K31/4412; A61K31/445; A61K31/4523; A61K31/47; A61K31/472; A61K31/50; A61K31/505; A61K31/517; A61K31/53; A61K31/662; A61P7/00; A61P9/10; A61P25/00; A61P29/00; A61P37/02; C07C237/22; C07C311/09; C07D207/16; C07D209/42; C07D209/48; C07D211/60; C07D211/86; C07D213/64; C07D215/20; C07D215/22; C07D215/227; C07D215/233; C07D215/24; C07D215/26; C07D217/24; C07D217/26; C07D231/06; C07D231/20; C07D233/84; C07D235/26; C07D235/28; C07D237/14; C07D239/34; C07D239/38; C07D239/88; C07D249/12; C07D249/18; C07D253/08; C07D257/04; C07D261/12; C07D261/20; C07D265/02; C07D271/06; C07D271/10; C07D271/113; C07D277/06; C07D277/20; C07D277/36; C07D277/68; C07D277/74; C07D285/125; C07D307/79; C07D309/30; C07D309/38; C07D311/30; C07D311/46; C07D327/04; C07D333/34; C07D333/62; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07F9/32; C07K5/00; C07K5/02; C07K5/078; C07K5/097; C07D285/12; (IPC1-7): C07C237/22; A61K31/197; A61K31/222; A61K31/225; A61K31/343; A61K31/351; A61K31/352; A61K31/37; A61K31/381; A61K31/401; A61K31/4035; A61K31/404; A61K31/41; A61K31/415; A61K31/4164; A61K31/4184; A61K31/4196; A61K31/42; A61K31/423; A61K31/4245; A61K31/426; A61K31/428; A61K31/433; A61K31/4402; A61K31/4412; A61K31/445; A61K31/4523; A61K31/47; A61K31/472; A61K31/50; A61K31/505; A61K31/517; A61K31/53; A61K31/662; A61P7/00; A61P9/10; A61P25/00; A61P29/00; A61P37/02; C07C311/09; C07D207/16; C07D209/42; C07D209/48; C07D211/60; C07D213/64; C07D215/20; C07D215/22; C07D215/24; C07D215/26; C07D217/24; C07D217/26; C07D231/20; C07D233/84; C07D235/28; C07D237/14; C07D239/34; C07D239/38; C07D239/88; C07D249/12; C07D249/18; C07D253/08; C07D257/04; C07D261/12; C07D261/20; C07D271/06; C07D271/10; C07D277/06; C07D277/36; C07D277/68; C07D277/74; C07D285/125; C07D307/79; C07D309/38; C07D311/30; C07D311/46; C07D327/04; C07D401/12; C07D401/14; C07D403/12; C07D403/14; C07D405/12; C07F9/32; C07K5/00
Attorney, Agent or Firm:
Takashi Ishida (4 others)