【発明の名称】イミダゾ-ル誘導体およびその製法

Title:

【発明の名称】イミダゾ-ル誘導体およびその製法

Document Type and Number:

Japanese Patent JPH07110854

Kind Code:

B2

Abstract:

Azole derivative of the general formula (I) in which A, L, O, R<1>, X, Y, Z and q have the meanings given, a process for their preparation, pharmaceutical preparations and the use of the compounds are described. Azole derivatives of the formula I where the symbols have, for example, the following meanings: R<1> = (C2-C10)-alkyl Z = nitrogen X and Y = independently of one another CR<2> L = -CH2- q = zero or 1 A = biphenyl radical which is substituted, for example, by R<15> R<2> = halogen or hydrogen R<15> = SO2-NH-CO-OR<6> and R<6> = phenyl, are highly active antagonists of angiotensin II receptors.

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Inventors:

Adalbert Wergner
Heinrich Englelt
Heinto Two Elner Kleman
Hermann gerhartz
Bernvealto Cielkens
Reinhard Betzker
Wolfgang Linz
Jean-Claude Carille
Jiyan-Paul Vouveil

Application Number:

JP1742392A

Publication Date:

November 29, 1995

Filing Date:

January 04, 1992

Export Citation:

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Assignee:

HOECHST AKTIENGESELLSCHAFT

International Classes:

A61K31/415; A61K31/425; A61K31/435; A61K31/44; A61K31/4427; A61K31/443; A61K31/4433; A61K31/445; A61K31/505; A61K31/535; A61K31/54; A61K31/64; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P13/02; A61K31/40; A61P15/00; A61P43/00; C07D207/34; C07D207/36; C07D233/54; C07D233/66; C07D233/68; C07D233/70; C07D233/84; C07D233/90; C07D249/02; C07D255/02; C07D257/02; C07D257/04; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D417/12; C07D453/02; C07D521/00; (IPC1-7): C07D233/68; A61K31/415; A61K31/425; A61K31/435; A61K31/44; A61K31/445; A61K31/505; A61K31/535; A61K31/54; A61K31/64; C07D233/84; C07D233/90; C07D401/12; C07D403/12; C07D405/12; C07D417/12; C07D453/02

Domestic Patent References:

JP6323868A
JP1117876A
JP128071A

Attorney, Agent or Firm:

Chika Takagi (2 outside)

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