Title:
【発明の名称】クローン化したビタミンD結合タンパク質由来の大食細胞活性化因子
Document Type and Number:
Japanese Patent JPH11511962
Kind Code:
A
Abstract:
A process for producing a cloned macrophage activating factor (GcMAFc) comprises the steps of: a) cloning a Gc1 isoform into a baculovirus vector; b) expressing the cloned Gc1 isoform thereby producing the cloned protein (Gc1), wherein the Gc1 protein comprises approximately 458 amino acids with a molecular weight of approximately 52000 Da and three distinct domains, c) contacting cloned Gc protein in vitro with immobilized beta -galactosidase and sialidase; and d) obtaining the cloned macrophage activating factor (GcMAFc).
Inventors:
Yamamoto Nobuto
Application Number:
JP50133797A
Publication Date:
October 19, 1999
Filing Date:
June 05, 1996
Export Citation:
Assignee:
Yamamoto Nobuto
International Classes:
A61K31/00; A61K38/00; A61P19/00; A61P19/08; A61P19/10; A61P31/00; A61P31/12; A61P35/00; C07K14/47; C07K14/52; C07K14/57; C07K14/705; C12N9/38; C12N15/09; C12N15/12; C12N15/19; C12P21/02; C12Q1/34; C12Q1/40; G01N33/569; G01N33/573; G01N33/574; A61K39/00; (IPC1-7): C12N15/09; A61K31/00; A61K38/00; C07K14/52; C07K14/705; C12P21/02; C12Q1/40; G01N33/573; G01N33/574
Attorney, Agent or Firm:
Kazuo Shamoto (4 outside)