Title:
【発明の名称】マトリックスメタロプロテアーゼ阻害因子
Document Type and Number:
Japanese Patent JPH10509719
Kind Code:
A
Abstract:
Compounds of formula (I) and their pharmaceutically acceptable salts inhibit matrix metalloproteases, such as stromelysin, gelatinase, matrilysin and collagenase, and are useful in the treatment of mammals having disease-states alleviated by the inhibition of such matrix metalloproteases.
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Inventors:
Castellano, Erlind El
Bender, Stephen El
Deal, Judith Gee
Horn, steven
Riak, ten jay
Yuan, Jengyu
Bender, Stephen El
Deal, Judith Gee
Horn, steven
Riak, ten jay
Yuan, Jengyu
Application Number:
JP51710996A
Publication Date:
September 22, 1998
Filing Date:
November 21, 1995
Export Citation:
Assignee:
SYNTEX(U.S.A.)INCORPORATED
Agoron Pharmaceuticals Incorporated
Agoron Pharmaceuticals Incorporated
International Classes:
A61K31/16; A61K31/165; A61K31/195; A61K31/215; A61K31/235; A61K31/27; A61K31/34; A61K31/343; A61K31/38; A61K31/381; A61K31/397; A61K31/403; A61K31/404; A61K31/405; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/66; A61K31/662; A61K38/00; A61P1/02; A61P3/08; C07D213/82; A61P3/10; A61P27/02; A61P29/00; A61P35/00; A61P43/00; C07C51/60; C07C53/42; C07C57/72; C07C67/313; C07C67/317; C07C69/353; C07C69/533; C07C231/02; C07C233/47; C07C237/22; C07C237/42; C07C255/57; C07C255/60; C07C259/06; C07C271/20; C07C271/22; C07C279/14; C07C311/46; C07C317/38; C07C317/40; C07C323/52; C07C323/59; C07C323/60; C07C323/63; C07C327/12; C07C327/22; C07C327/30; C07C327/32; C07D205/08; C07D209/20; C07D213/75; C07D213/80; C07D263/22; C07D263/26; C07D295/13; C07D307/91; C07D333/76; C07F9/30; C07F9/32; C07F9/34; C07F9/36; C07F9/48; C07F9/58; C07F9/60; C07F9/62; C07F9/6558; C07K5/023; (IPC1-7): C07C237/22; C07K5/023; C07F9/60; C07D333/76; C07D307/91; C07D263/22; C07D213/80; C07D213/75; C07D209/20; C07D205/08; C07C327/32; C07C323/60; C07C271/20; C07C231/02; A61K38/00; A61K31/66; A61K31/44; A61K31/405; A61K31/38; A61K31/34; A61K31/27; A61K31/215; A61K31/165
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)