Title:
【発明の名称】NMR構造を決定するための方法及び組生物
Document Type and Number:
Japanese Patent JP2001514239
Kind Code:
A
Abstract:
This invention is concerned with determining the three-dimensional structure of biological macromolecules such as proteins. In particular, it is concerned with methods for rapidly determining protein structure by NMR, by providing methods for simplifying NMR spectra using labeled proteins prepared from specifically isotopically labeled amino acids having at least two isotopes of 13C, 15N and 2H in the backbone, and methods for making these labeled proteins, e.g., by cultivation of a microbial culture containing said labeled amino acids.
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Inventors:
Anderson Frank Elbert The Third
Brown Jonathan Miles
Colin Philip Edward
Homan's Stephen William
Weller Charles Tobias
Zimmerman-Wilson Carey Anne
Oliver Eddie James Jr.
Brown Jonathan Miles
Colin Philip Edward
Homan's Stephen William
Weller Charles Tobias
Zimmerman-Wilson Carey Anne
Oliver Eddie James Jr.
Application Number:
JP2000508633A
Publication Date:
September 11, 2001
Filing Date:
September 02, 1998
Export Citation:
Assignee:
Martek Corporation
International Classes:
C07B43/06; C07B59/00; C07K14/00; C07K14/59; C12N1/20; C12N5/00; C12N5/02; C12N5/07; G01N24/08; C12N5/071; C12N5/077; C12P21/00; C12P21/02; G01N33/68; G01R33/465; (IPC1-7): C07K14/00; C07B43/06; C07B59/00; C12N1/20; C12N5/06; C12P21/02; G01N24/08; G01N33/68
Attorney, Agent or Firm:
Hiroaki Tazawa (1 person outside)