Title:
【発明の名称】増殖能を増強しかつ複製老化を防止する方法及び試薬
Document Type and Number:
Japanese Patent JP2002530436
Kind Code:
A
Abstract:
The present invention relates to methods and reagents for extending the life-span, e.g. the number of mitotic divisions, of a cell. In general, the subject method relies on the activation of a telomerase activity and inhibition of one or both of an Rb/p16 pathway or a p53 pathway.
Inventors:
Gregory Jay Hannon
David H. Beach
David H. Beach
Application Number:
JP2000584049A
Publication Date:
September 17, 2002
Filing Date:
November 24, 1999
Export Citation:
Assignee:
Genetica Incorporated
International Classes:
A61K8/96; A61K8/98; A61K35/12; A61K38/17; A61K38/22; A61K45/00; A61K45/06; A61K48/00; C12N15/09; A61P43/00; A61Q19/08; C12N9/12; (IPC1-7): A61K35/12; A61K7/00; A61K38/22; A61K45/00; A61K48/00; A61P43/00; C12N15/09
Attorney, Agent or Firm:
Motohiro Kurauchi (1 outside)