【発明の名称】循環ガン細胞の迅速かつ効率的な単離のための方法および試薬

Japanese Patent JP2002503814

A

A highly sensitive assay is disclosed which combines immunomagnetic enrichment with multiparameter flow cytometric and immunocytochemical analysis to detect, enumerate and characterize carcinoma cells in the blood. The assay can detect one epithelial cell or less in 1 ml of blood and has a greater sensitivity than conventional PCR or immunohistochemistry by 1-2 orders of magnitude. In addition, the assay facilitates the biological characterization and staging of carcinoma cells.

WO/2001/096857	METHOD AND APPARATUS FOR COMBINED MAGNETOPHORETIC AND DIELECTROPHORETIC MANIPULATION OF ANALYTE MIXTURES
WO/2014/016170	METHOD FOR MAGNETIC SEPARATION OF PRECIPITATION PRODUCTS FROM FLUIDS USING REUSABLE SUPERPARAMAGNETIC COMPOSITE PARTICLES
JP3297046	INDUSTRIAL APPLICABILITY Biodegradable particle coating having a protein covalently immobilized by a cross-linking agent.

Leon W. M. M. Tarstappen
Gala Chandra Lao
Jonathan W. Wu
Emilian Buoy Lasila
Paul A. Liberty

JP2000531745A

February 05, 2002

February 12, 1999

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IMMUNIVEST CORPORATION
Board of Regents, The University of Texas System

B03C1/01; C12Q1/02; C12Q1/06; C12Q1/24; G01N33/48; G01N33/58; G01N33/53; G01N33/543; G01N33/574; H01F1/00; (IPC1-7): G01N33/58; C12Q1/06; C12Q1/24; G01N33/53; G01N33/574

Aoyama Ryo (1 person outside)

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