Title:
【発明の名称】ヒト免疫不全ウイルス(HIV)の検出と治療のための方法および物質
Document Type and Number:
Japanese Patent JP2583555
Kind Code:
B2
Abstract:
Disclosed are immunologically active polypeptides, preferably antibodies or antibody fragments, and most preferably monoclonal antibodies, which are reactive with idiotypes of antibodies to human lymphocyte T4 protein and are reactive with the HIV virion in a manner allowing for in vitro and in vivo neutralization of HIV infectivity and detection of HIV particles in biological fluids. Presently preferred embodiments comprise monoclonal anti-monoclonal-anti-human lymphocyte T4 antibodies produced by new murine hybridoma cell lines JT4CB, JT4C12, JT4C16, JT1-1F3, JT1-1F3-E5, JT1-1D7 and JT2-N15. Also disclosed are active and passave vaccination procedures.
Inventors:
OONO NORYA
Application Number:
JP3825888A
Publication Date:
February 19, 1997
Filing Date:
February 19, 1988
Export Citation:
Assignee:
NISSIN FOOD PRODUCTS LTD
International Classes:
G01N33/569; A61K39/21; A61K39/395; A61K39/42; C07K14/005; C07K14/155; C07K14/16; C07K14/195; C07K14/435; C07K16/00; C07K16/10; C07K16/42; C07K19/00; C12N1/20; C12N5/10; C12N15/02; C12N15/09; C12N15/49; C12P21/00; C12P21/08; G01N33/577; A61K38/00; A61K39/00; C12R1/91; (IPC1-7): C12P21/08; A61K39/395; C07K14/16; C07K16/10; C12N5/10; C12N15/02; G01N33/569; G01N33/577
Domestic Patent References:
| JP61286756A |
Other References:
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Attorney, Agent or Firm:
Yoshihiro Tsunoda