Title:
【発明の名称】核酸及びウイルス性病原体をコントロールするためのこれらの使用方法
Document Type and Number:
Japanese Patent JPH08500971
Kind Code:
A
Abstract:
The invention consists of a non-naturally occurring nucleic acid molecule capable of blocking or interfering with a replicative intermediate of a virus, a virusoid, or a viroid. The nucleic acid molecule may contain a ribozyme or a plurality of ribozymes. Alternatively, the nucleic acid molecule may be an antisense nucleic acid molecule. The ribozyme may be a hairpin ribozyme, a hammerhead ribozyme, an RNAase P ribozyme, a minizyme, or other catalytic RNA molecule. The virus may be an animal, a mammalian, a plant, a fungal, a protozoan, a yeast, a bacterial virus, or a human virus. The nucleic acid molecule may be expressed in the cell or it may be preformed and administered (ex vivo). The present invention contemplates methods of controlling infection of a pathogenic infectious agent in a plant or animal.
Inventors:
Atkins, David G
Garrack, Wayne El
Young, Mark Jay
Garrack, Wayne El
Young, Mark Jay
Application Number:
JP50262293A
Publication Date:
February 06, 1996
Filing Date:
June 29, 1993
Export Citation:
Assignee:
Gene Sears Pty Limited
International Classes:
C12N15/09; A01N57/16; C12N5/10; C12N7/00; C12N15/113; C12N15/82; (IPC1-7): C12N15/09; C12N5/10
Attorney, Agent or Firm:
Takehiko Suzue (3 outside)