Title:
【発明の名称】内皮細胞カドヘリン類に特異的なモノクローナル抗体およびそれらの用途
Document Type and Number:
Japanese Patent JP2002512505
Kind Code:
A
Abstract:
A new VE-cadherin molecule is provided. Monoclonal antibodies that specifically bind to and neutralize an extracellular domain of a VE-cadherin molecule are provided. In vitro and in vivo methods of using these antibodies are also provided.
Inventors:
Dejana, Elisabetta
Terrorism, paola
Terrorism, paola
Application Number:
JP52665598A
Publication Date:
April 23, 2002
Filing Date:
November 05, 1997
Export Citation:
Assignee:
ImClone Systems, Inc.
International Classes:
G01N33/53; A61K31/337; A61K31/704; A61K33/24; A61K38/00; A61K39/395; A61P9/00; A61P35/00; C07H15/252; C07K14/47; C07K14/705; C07K16/18; C07K16/28; C07K16/46; C12N5/10; C12N15/09; C12P21/08; (IPC1-7): C12N15/09; A61K31/337; A61K31/704; A61K33/24; A61K38/00; A61K39/395; A61P9/00; A61P35/00; C07K14/47; C07K16/18; C07K16/46; C12N5/10; C12P21/08; G01N33/53
Attorney, Agent or Firm:
Miyuki Ariga (4 outside)