Title:
【発明の名称】第Xa因子のインヒビターとしてのN-置換グリシン誘導体
Document Type and Number:
Japanese Patent JPH10512550
Kind Code:
A
Abstract:
The present invention discloses peptide aldehydes which are potent inhibitors of factor Xa, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
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Inventors:
Ableman, Matthew Mark
Miller, Todd Anthony
Nut, Loose Faucher
Miller, Todd Anthony
Nut, Loose Faucher
Application Number:
JP52003196A
Publication Date:
December 02, 1998
Filing Date:
December 21, 1995
Export Citation:
Assignee:
Corbus International, Incorporated
International Classes:
A61K38/00; A61P7/02; C07C311/10; C07C311/13; C07C317/48; C07C317/50; C07C323/58; C07C323/59; C07C323/60; C07D211/56; C07D211/74; C07D213/56; C07D401/12; C07D451/02; C07K5/06; C07K5/072; C07K5/078; (IPC1-7): C07K5/06; A61K38/00
Attorney, Agent or Firm:
Shusaku Yamamoto