Title:
【発明の名称】新規N-ベンジル-N1-フェニル-および-フェナルキル-チオ尿素類
Document Type and Number:
Japanese Patent JPH0753708
Kind Code:
B2
Abstract:
Compounds of formula II wherein one of R1 and R2 is branched lower alkyl and the other is hydrogen or branched lower alkyl, R3 is hydrogen or C1-4alkyl, R4 and R5 are hydrogen, halogen, C1-5alkyl, substituted C1-5alkyl, aryl, substituted or unsubstituted aryl or a group of formula, -COOH, -COOR8 or -CONR9R10, wherein R8 is C1-5alkyl and R9 and R10 are, independently, hydrogen or C1-5alkyl, R6 and R7 have the meanings given for R4 and R5 or, together with the carbon atom to which they are attached, form a substituted or unsubstituted C3-7cyclo-alkyl group, R is -O-, -S- or -NH- and X is -(CH2)n- wherein n is zero, 1, 2 or 3, and their physiologically hydrolysable and acceptable esters and amides and pharmaceutically acceptable salts thereof, processes for their production and pharmaceutical compositions comprising them.
Inventors:
Christopher Simon John Walpole
Roger Uliglesworth
Roger Uliglesworth
Application Number:
JP14478991A
Publication Date:
June 07, 1995
Filing Date:
June 17, 1991
Export Citation:
Assignee:
SANDOZ AKTIENGESELLSCHAFT
International Classes:
A61K31/195; A61K31/215; A61P25/04; A61P29/00; A61K31/17; C07C335/12; (IPC1-7): C07C335/12; A61K31/17; A61K31/195; A61K31/215
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)
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