Title:
【発明の名称】診断および治療用の新規キノリン配位子および金属錯体
Document Type and Number:
Japanese Patent JP2003525282
Kind Code:
A
Abstract:
The present invention relates to novel ligands for forming metal complexes that absorb or fluoresce in the visible or near-infrared (NIR) region of the electromagnetic spectrum, new complexes incorporating such ligands, process for preparing such complexes, and methods of imaging or therapy using such agents. More particularly, the present invention specifically pertains to novel metal complexes derived from quinoline based heterocyclic N2O3, N3O3, N3O4, N3O5 and N2OS ligands, and are useful as general imaging, diagnostic, or therapeutic agents employing optical, nuclear medicine, or magnetic resonance procedures.
Inventors:
Ragaban Rajago Paran
Samuel I Achirev
Joseph E. Bugaju
Richard B. Doshaw
Samuel I Achirev
Joseph E. Bugaju
Richard B. Doshaw
Application Number:
JP2001563501A
Publication Date:
August 26, 2003
Filing Date:
February 28, 2001
Export Citation:
Assignee:
Mallinckrodt INC.
International Classes:
A61K31/47; A61K49/00; A61K49/04; A61P31/00; A61P35/00; C07D215/26; C07D215/30; C07F13/00; (IPC1-7): C07D215/26; A61K31/47; A61K49/00; A61K49/04; A61P31/00; A61P35/00; C07D215/30
Domestic Patent References:
| JPH04502574A | 1992-05-14 |
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)