Title:
【発明の名称】遺伝子制御のための核酸配列およびその使用方法
Document Type and Number:
Japanese Patent JP2003527081
Kind Code:
A
Abstract:
The invention provides nucleic acid sequences which regulate expression of a nucleotide sequence of interest. In particular, the invention provides nucleic acid sequences which regulate expression of a nucleotide sequence of interest in an age-related manner and/or in a liver-specific manner. The invention further provides methods of using the regulatory nucleic acid sequences provided herein for age-related and/or liver-specific expression of nucleotides seuqences of interest. The invention also provides host cells and transgenic non-human animals which harbor the regulatory nucleic acid sequences of the invention. The compositions and methods of the invention are useful in regulating expression of a nucleotide sequence of interest in an age-related and/or liver-specific manner.
Inventors:
Kurachi, Kotoku
Kurachi, Sumiko
Kurachi, Sumiko
Application Number:
JP2001502546A
Publication Date:
September 16, 2003
Filing Date:
June 06, 2000
Export Citation:
Assignee:
Regents of the University of Michigan
International Classes:
C12N15/09; A61K31/7088; A61K38/00; A61K39/395; A61K48/00; A61P1/16; A61P3/10; A61P7/02; A61P9/10; A61P19/02; A61P19/10; A61P25/16; A61P25/28; A61P35/00; C07K14/47; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/64; (IPC1-7): C12N15/09; A61K31/7088; A61K38/00; A61K48/00; A61P1/16; A61P3/10; A61P7/02; A61P9/10; A61P19/02; A61P19/10; A61P25/16; A61P25/28; A61P35/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10
Attorney, Agent or Firm:
Yusuke Hiraki (2 outside)