Title:
【発明の名称】ニューロン損傷の処置または予防のためのピペラジンおよびピペリジン誘導体
Document Type and Number:
Japanese Patent JP2003522767
Kind Code:
A
Abstract:
The present invention relates to piperazine and piperidine derivatives, which are especially useful for treating or preventing neuronal damage, particularly damage associated with neurological diseases. These compounds are also useful for stimulating nerve growth. The invention also provides compositions comprising the compounds of the present invention and methods of utilizing those compositions for treating or preventing neuronal damage or for stimulating nerve growth.
Inventors:
Ronald Tomlinson
Laufer, David
Mulican, Michael
Laufer, David
Mulican, Michael
Application Number:
JP2001558441A
Publication Date:
July 29, 2003
Filing Date:
February 09, 2001
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
A61K31/40; A61K31/4025; A61K31/427; A61K31/4523; A61K31/454; A61K31/4545; A61K31/496; A61K31/4995; A61K31/506; A61K38/22; A61K38/27; A61P19/04; A61P21/00; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/14; A61P25/16; A61P25/28; A61P29/00; C07D205/04; C07D207/16; C07D209/52; C07D211/26; C07D211/60; C07D211/62; C07D211/78; C07D277/06; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D405/12; C07D405/14; C07D409/12; C07D409/14; C07D417/06; C07D417/12; C07D487/08; C07D; (IPC1-7): C07D205/04; A61K31/40; A61K31/4523; A61K31/454; A61K31/4545; A61K31/496; A61K31/4995; A61K31/506; A61K38/22; A61K38/27; A61P19/04; A61P21/04; A61P25/00; A61P25/02; A61P25/04; A61P25/14; A61P25/16; A61P25/28; C07D207/16; C07D209/52; C07D211/26; C07D211/60; C07D211/62; C07D211/78; C07D277/06; C07D401/06; C07D401/12; C07D405/12; C07D409/12; C07D417/06; C07D417/12; C07D487/08
Domestic Patent References:
| JPH11106375A | 1999-04-20 | |||
| JPS62192358A | 1987-08-22 |
Foreign References:
| WO1998025950A1 | 1998-06-18 | |||
| US3862937A | 1975-01-28 | |||
| US5102882A | 1992-04-07 |
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)