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Patent Searching and Data


Title:
【発明の名称】高眼圧処置剤としてのシ?ロ?ン?ンヘプ?ン(エン)酸,2-ヘテロアリールアルケニル誘導体
Document Type and Number:
Japanese Patent JPH11505802
Kind Code:
A
Abstract:
The invention relates to the use of derivatives of F-type prostaglandins as ocular hypotensives. The PGF derivatives used in accordance with the invention are represented by formula (I), wherein wavy line attachments indicate either the alpha alpha or beta beta configuration; hatched segments indicate alpha configuration; solid triangles are used to indicate beta configuration, dashed bonds represent a double bond, or a single bond, R is a substituted heteroaryl radical, R<1> is hydrogen or a lower alkyl radical having up to six carbon atoms, X is selected from the group consisting of -OR<1> and -N(R<1>)2, Y is = O or represents 2 hydrogen radicals. Certain of the compounds represented by formula (I) comprise another aspect of the present invention.

Inventors:
Bar?, Robert E?
Application Number:
JP53497196A
Publication Date:
May 25, 1999
Filing Date:
May 14, 1996
Export Citation:
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Assignee:
Alert
International Classes:
C07D333/16; A61K31/38; A61K31/381; A61K31/42; A61K31/421; A61K31/425; A61K31/426; A61K31/557; A61K31/5575; A61P27/02; A61P27/06; C07C405/00; C07D263/30; C07D277/24; C07D277/30; C07D307/54; C07D307/79; C07D333/24; C07D333/28; C07D333/32; C07D333/56; C07D333/60; (IPC1-7): C07C405/00; A61K31/38; A61K31/42; A61K31/425; A61K31/557; C07D263/30; C07D277/24; C07D307/54; C07D333/16; C07D333/28; C07D333/56
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)