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Title:
【発明の名称】トラマドールサッカリナートを含有する徐放性投薬形
Document Type and Number:
Japanese Patent JP2003508430
Kind Code:
A
Abstract:
A controlled-release oral dosage formulation of a salt-forming active ingredient, wherein the active ingredient is present as at least two different salts in a solid aggregation state, wherein the two different salts have different water solubility and release the active ingredient in-vitro at different release rates, provided that oral dosage formulations are excluded which comprise a resin carrying a sulfonate group and a resin carrying a carboxyl group and which contain an active ingredient in a form fixed to these resins.

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Inventors:
Baltic Horomeus Johannes
Kugelmann Heinrich
Ziegrel Iris
Application Number:
JP2001519897A
Publication Date:
March 04, 2003
Filing Date:
August 03, 2000
Export Citation:
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Assignee:
Grunenthal Gesellschaft Mito Beschlenktel Haftung
International Classes:
A61K9/16; A61K9/20; A61K9/22; A61K9/26; A61K9/28; A61K9/48; A61K9/50; A61K9/52; A61K9/68; A61K31/135; A61K31/19; A61K31/195; A61K31/205; A61K31/428; A61K31/54; A61K31/60; A61K47/12; A61K47/14; A61K47/32; A61K47/34; A61K47/38; A61K47/44; A61K9/10; A61P1/04; A61P1/12; A61P9/00; A61P11/00; A61P11/14; A61P13/00; A61P25/08; A61P25/14; A61P25/18; A61P25/24; A61P25/30; A61P29/00; A61P37/08; C07C217/74; C07C307/02; C07D275/06; C07D291/06; A61K9/00; (IPC1-7): A61K31/135; A61K9/10; A61K9/16; A61K9/26; A61K9/52; A61K31/428; A61K47/14; A61K47/32; A61K47/38; A61K47/44; A61P1/04; A61P1/12; A61P9/00; A61P11/00; A61P11/14; A61P13/00; A61P25/08; A61P25/14; A61P25/18; A61P25/24; A61P25/30; A61P29/00; A61P37/08
Attorney, Agent or Firm:
Mitsufumi Ezaki (3 others)



 
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