Title:
【発明の名称】合成ポリサッカライド、それらの製造法およびそれらを含む医薬組成物
Document Type and Number:
Japanese Patent JP3345020
Kind Code:
B2
Abstract:
A synthetic polysaccharide including an antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin binding domain including a concatenation of 10-25 monosaccharide units selected from hexoses, pentoses or deoxy sugars of which all the hydroxyl groups are etherified by a C1-6 alkyl group or esterified in the form of sulpho groups, as well as salts and particularly pharmaceutically acceptable salts thereof, are disclosed.
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Inventors:
Dorige, Pierre Alexandre
Duchosoi, Philip
Herbert, Jean-Marc
Petite, Maurice
Van Bouker, Constant
Flotenface, Peter
Draf-Tromp, Cornelia
Basten, Johannes
Duchosoi, Philip
Herbert, Jean-Marc
Petite, Maurice
Van Bouker, Constant
Flotenface, Peter
Draf-Tromp, Cornelia
Basten, Johannes
Application Number:
JP50665198A
Publication Date:
November 18, 2002
Filing Date:
July 18, 1997
Export Citation:
Assignee:
Sanofi sante lab
Akzo Novel Namrose Fennaught Shap
Akzo Novel Namrose Fennaught Shap
International Classes:
A61K31/00; A61K31/7028; A61K31/7042; A61K31/7048; A61K31/715; A61K31/727; C07H15/00; A61K31/737; A61P7/00; A61P7/02; C07H3/04; C07H7/033; C07H11/00; C07H15/04; C07H19/01; C08B37/00; C08B37/10; (IPC1-7): C08B37/00; A61K31/715; A61P7/02; C07H15/00; C07H15/04; C07H19/01
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)