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Title:
【発明の名称】デヒドロエピアンドロステロンの治療用途およびデリバリーシステム
Document Type and Number:
Japanese Patent JP3441730
Kind Code:
B2
Abstract:
Sex steroid precursors such as dehydroepiandrosterone and dehydroepiandrosterone sulphate, and compounds converted in vivo to either of the foregoing, are utilized for the treatment and/or prevention of vaginal atrophy, hypogonadism, diminished libido, osteoporosis, urinary incontinence, ovarian cancer, uterine cancer, skin atrophy, for contraception, and, in combination with an estrogen and/or progestin, for the treatment of menopause. The precursors may be formulated for percutaneous or transmucosal administration. Gels, solutions, lotions, creams, ointments and transdermal patches for the administration of these precursors are provided, as are certain pharmaceutical compositions and kits which can be used for the prevention and treatment of a wide variety of conditions related to decreased secretion of sex steroid precursors by the adrenals.

Inventors:
Laburi, Fernand
Application Number:
JP51650994A
Publication Date:
September 02, 2003
Filing Date:
January 19, 1994
Export Citation:
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Assignee:
ENDORECHERCHE, INC.
International Classes:
A61K8/63; A61K9/00; A61K9/70; A61K31/565; A61K31/57; A61K31/58; A61P5/00; A61P15/00; A61P15/02; A61P17/00; A61P25/00; A61Q19/00; C07J1/00; C07J17/00; C07J43/00; (IPC1-7): A61K31/565; A61K31/57; A61K31/58; A61P15/02; A61P17/00; C07J43/00
Domestic Patent References:
JP3209328A
Other References:
【文献】米国特許4978532(US,A)
【文献】米国特許5047244(US,A)
【文献】米国特許4835147(US,A)
【文献】米国特許4496556(US,A)
【文献】米国特許4518595(US,A)
【文献】米国特許3661941(US,A)
【文献】英国特許1246639(GB,B)
【文献】Chemical Abstracts,84:119433
Attorney, Agent or Firm:
Fukami Hisaro (3 outside)