Title:
【発明の名称】抗腫瘍性蛋白質
Document Type and Number:
Japanese Patent JP2759457
Kind Code:
B2
Abstract:
Physiologically active proteins having the following properties: (1) having a molecular weight (determined by gel filtration with Sephadex G-75) of 4,000 to 15,000; (2) obtainable from the water-soluble fraction of protozoan Toxoplasma; (3) showing an anti-tumor activity against sarcoma transplanted on mouse. The above proteins can be purified with a high efficiency by reverse phase liquid chromatography. Further, the purified proteins are useful as anti-tumor agents.
Inventors:
SUZUKI NAOYOSHI
YOSHIDA YUTAKA
OZAKI FUMIO
KOJIMA SHINICHI
YANAGI YOSHIKAZU
SUWA KAZUYUKI
YOSHIDA YUTAKA
OZAKI FUMIO
KOJIMA SHINICHI
YANAGI YOSHIKAZU
SUWA KAZUYUKI
Application Number:
JP11788788A
Publication Date:
May 28, 1998
Filing Date:
May 13, 1988
Export Citation:
Assignee:
SUMITOMO SEIYAKU KK
International Classes:
C12P21/00; A61K38/00; A61P35/00; C07K1/20; C07K14/00; C07K14/005; C07K14/195; C07K14/44; C07K14/45; C12R1/90; (IPC1-7): C07K14/45; A61K38/00; C07K1/20
Other References:
BIOCHEMISTRY=1975
Attorney, Agent or Firm:
Takashima Hajime