Title:
【発明の名称】2―(2―オキソ―エチリデン)―イミダゾリジン―4―オンの誘導体およびファルネシル蛋白質トランスフェラーゼ阻害物質としてのそれらの使用法
Document Type and Number:
Japanese Patent JPH11512750
Kind Code:
A
Abstract:
PCT No. PCT/IB97/00584 Sec. 371 Date Oct. 7, 1999 Sec. 102(e) Date Oct. 7, 1999 PCT Filed May 22, 1997 PCT Pub. No. WO97/49700 PCT Pub. Date Dec. 31, 1997The present invention relates to compounds of the formula wherein R1, R2, R3 and R4 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula I to said mammal.
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Inventors:
Rishikatos, Joseph, Peter
Application Number:
JP53656197A
Publication Date:
November 02, 1999
Filing Date:
May 22, 1997
Export Citation:
Assignee:
Pfizer Inc.
International Classes:
A61K31/00; A61K31/44; A61K31/4427; A61K31/4439; A61P35/00; A61P43/00; C07D401/14; (IPC1-7): C07D401/14; A61K31/00; A61K31/44
Attorney, Agent or Firm:
Hiroshi Kobayashi
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