Title:
【発明の名称】ジベンゾジヒドロピリジンカルボン酸エステル類及びそれらの化学ルミネセント分析法への利用
Document Type and Number:
Japanese Patent JP3338061
Kind Code:
B2
Abstract:
PCT No. PCT/NL97/00417 Sec. 371 Date Jan. 7, 1999 Sec. 102(e) Date Jan. 7, 1999 PCT Filed Jul. 15, 1997 PCT Pub. No. WO98/02421 PCT Pub. Date Jan. 22, 1998Dibenzodihydropyridinecarboxylic esters are provided which comply with formula (1) or (2), wherein: R1 is substituted alkyl or cyano; R2 and R3 are independently hydrogen, alkyl, substituted alkyl, aryl or substituted aryl; R4 is hydrogen, alkyl, substituted alkyl, aryl or substituted aryl; R5 and R6 are independently alkyl, alkoxy or another substituent which is relatively resistant to oxidation; m and n are integers from 0 to 4; wherein, if m or n is at least 2, two groups R5 or R6 may be linked together; and Z is oxygen or sulphur. The new compounds are used in a method as chemiluminogenic reagents for detecting the presence of peroxidase activity at extremely low levels (10-20 moles). A kit containing the dibenzodihydropyridine-carboxylic esters for use in assaying peroxidase activity has also been described.
Inventors:
Yakumuns, Marjorie
Somer, Gusberth
Somer, Gusberth
Application Number:
JP50588198A
Publication Date:
October 28, 2002
Filing Date:
July 15, 1997
Export Citation:
Assignee:
Netherlands country
International Classes:
C07D219/04; C07D221/12; C12Q1/28; G01N33/58; G01N21/78; (IPC1-7): C07D219/04; C07D221/12; C12Q1/28; G01N21/78
Domestic Patent References:
| JP6357572A | ||||
| JP2503268A | ||||
| JP8500125A |
Other References:
Ｐｈｏｔｏｃｈｅｍｉｓｔｒｙ ａｎｄ Ｐｈｏｔｏｂｉｏｌｏｇｙ，１９６５年，Ｖｏｌ．４，Ｐ．１１１１−１１２１
Attorney, Agent or Firm:
Akira Asamura (3 outside)