Title:
【発明の名称】内皮単球活性化ポリペプチド▲II▼:宿主の応答を活性化するメディエーター
Document Type and Number:
Japanese Patent JPH09505987
Kind Code:
A
Abstract:
This invention provides a purified endothelial monocyte activating polypeptide (EMAP II). It further provides a method of obtaining purified endothelial monocyte activating polypeptide (EMAP II), a method of making antibodies to it and a method of detecting it. This invention also provides an effector cell activating protein which contains an amino acid sequence homologous to RIGRIVT and a method of detecting same. This invention also provides a method of treating a tumor in a subject by administering an effective dose of endothelial monocyte activating polypeptide (EMAP II).
Inventors:
Stern, David M
Claus, Machias
Khao, Janet
Kaiton, mark
Liberty, Stephen K.
Claus, Machias
Khao, Janet
Kaiton, mark
Liberty, Stephen K.
Application Number:
JP51046595A
Publication Date:
June 17, 1997
Filing Date:
September 29, 1994
Export Citation:
Assignee:
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61P35/00; A61P43/00; C07H21/04; C07K14/52; C07K16/24; C12N15/09; C12P21/02; C12P21/08; (IPC1-7): C12N15/09; A61K38/00; C07K14/52; C07K16/24; C12P21/02; C12P21/08; G01N33/53
Attorney, Agent or Firm:
Takehiko Suzue (3 outside)