Title:
【発明の名称】Fasリガンド融合タンパク質
Document Type and Number:
Japanese Patent JP2000500336
Kind Code:
A
Abstract:
A protein comprising the human Fas Ligand protein (hFasL) or a truncated human Fas Ligand protein or a functionally equivalent variant thereof that retain the Fas receptor-binding and apoptosis-inducing properties of hFasL and, linked either directly or indirectly to its C-terminus, a glycophospholipid is useful in preventing or treating tissue or organ graft rejection.
Inventors:
Buehler, thomas
Application Number:
JP51859697A
Publication Date:
January 18, 2000
Filing Date:
November 15, 1996
Export Citation:
Assignee:
Novartis Actien Gezel Shaft
International Classes:
C12N15/09; A61K31/00; A61K38/00; A61P37/00; A61P37/06; C07K1/113; C07K7/02; C07K14/705; C12N15/12; C12P9/00; C12P19/00; C12P21/02; (IPC1-7): C12N15/09; A61K38/00; A61P37/06; C07K1/113; C07K7/02; C07K14/705; C12P9/00; C12P19/00; C12P21/02
Domestic Patent References:
| JPH0590011A | 1993-04-09 | |||
| JPS6237145U | 1987-03-05 | |||
| JPH05332845A | 1993-12-17 |
Attorney, Agent or Firm:
Aoyama Ryo (2 outside people)