Title:
【発明の名称】高次第二銅酸塩錯体の製造法
Document Type and Number:
Japanese Patent JP2667875
Kind Code:
B2
Abstract:
This invention encompasses a process for preparing higher order cuprate complexes which contain a carbanion for the formation of carbon to carbon bonds in reactions such as 1,4-conjugate addition. The complex is formed by reacting a first cuprate complex with a stannane such that the carbanion to be used to form carbon to carbon bonds is transferred from the stannane to the first cuprate complex to form a different higher order cuprate complex. This process permits the in situ preparation of a higher order cuprate complex having the carbanion desired to be used in a synthetic reaction. Higher order cuprate complexes prepared by this process are particularly useful for the efficient preparation of pharmacologically active prostaglandins.
Inventors:
Arthur Lee Campbell
James Richard Bering
James Richard Bering
Application Number:
JP14144588A
Publication Date:
October 27, 1997
Filing Date:
June 08, 1988
Export Citation:
Assignee:
G.D.Searle & Company
International Classes:
C07B37/04; C07C67/00; C07C401/00; C07C405/00; C07F1/08; C07F7/18; C07F7/22; (IPC1-7): C07F1/08; C07B37/04; C07C405/00
Attorney, Agent or Firm:
Akira Asamura (2 outside)