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Title:
【発明の名称】オキシアルキン、これを含有する薬剤並びにこの化合物及び薬剤の製造方法
Document Type and Number:
Japanese Patent JP3345082
Kind Code:
B2
Abstract:
Oxyalkyne compounds corresponding to the formula Ia- or para-position is R1 represents CH3 or NH2, R2 represents H or CH3, R3 represents H, C1-3-alkyl or COCH3, and Ar represents an aromatic residue selected from the group with the proviso that the substituents R4, R5 and R6 are the same or different and each substituent represents H, F, Cl, Br, C1-6-alkyl, CF3 or C1-6-alkoxy, and R7 represents H, F, Cl, Br, C1-3-alkyl or CF3, in the form of their racemates or mixtures of diastereoisomers or in optically active form, which are suitable active ingredients in pharmaceutical compositions.

Inventors:
Ulrich Zaip
Werner Voorenberg
Werner Engleberger
Cornelia Geist
Michyaer Howlant
Application Number:
JP7054093A
Publication Date:
November 18, 2002
Filing Date:
March 29, 1993
Export Citation:
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Assignee:
Grunenthal Gesellschaft Mito Beschlenktel Haftung
International Classes:
A61K31/16; A61K31/22; A61K31/38; A61K31/381; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61P11/00; A61P43/00; C07C259/06; C07C275/24; C07C275/64; C07D213/42; C07D333/20; (IPC1-7): C07C259/06; A61K31/16; A61K31/22; A61K31/38; A61K31/44; A61P11/00; A61P43/00; C07C275/24; C07D213/42; C07D333/20
Domestic Patent References:
JP63284155A
JP4243856A
Attorney, Agent or Firm:
Mitsufumi Esaki (2 others)