【発明の名称】ピペリジニルカンホスルホニルオキシトシン拮抗剤

Title:

【発明の名称】ピペリジニルカンホスルホニルオキシトシン拮抗剤

Document Type and Number:

Japanese Patent JPH0751564

Kind Code:

B2

Abstract:

Spirocyclic compounds of the formula: are oxytocin and vasopressin antagonists useful in the treatment of pre-term labor, dysmenorrhea and for the stoppage of labor preparatory to cesarean delivery, timing of parturition, uterine hyperactivity, endometriosis, hypertension, congestive heart failure, hyponatremia and cognitive disorders.

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Inventors:

Mark Gee Bock
Ben E. Evans
Roger M. Fredinger
Kevin Gilbert
Doug W. Hobbes
George F. Randell
Douglas J. Petit Bone
Kenneth E. L

Application Number:

JP35263291A

Publication Date:

June 05, 1995

Filing Date:

November 13, 1991

Export Citation:

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Assignee:

Merck End-Campany Inc.

International Classes:

A61K31/50; A61K31/55; A61K31/675; A61P13/02; A61P15/00; C07D221/20; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D417/14; C07D419/12; A61K31/435; C07F9/576; C07K5/02; (IPC1-7): C07D221/20; A61K31/435; A61K31/50; A61K31/55; A61K31/675; C07D401/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07D417/14; C07F9/576; C07K5/02

Attorney, Agent or Firm:

Masao Okabe (6 others)

Next Patent: MOLDED ADSORBENT AND ITS MANUFACTURE