Title:
【発明の名称】系列特異性細胞および前駆体細胞
Document Type and Number:
Japanese Patent JP2002511246
Kind Code:
A
Abstract:
A method for generating a culture that is purified or enriched in respect of cells of a selected lineage is described in which a selectable marker, which is differentially expressed in cells of the selected lineage compared with its expression in other cells, is introduced into a multipotential cell and the multipotential cell is cultured to induce differentiation of the multipotential cell into a cell of the selected lineage or into a mixture of cells including cells of the selected lineage, or is cultured to induce preferential survival of cells of the selected lineage. Those cells that express the selectable marker are then selected for. Progenitors of selected lineage are also described as is the use of the method in assay techniques.
Inventors:
Smith, Austin
Lee, Mang
Lee, Mang
Application Number:
JP2000543570A
Publication Date:
April 16, 2002
Filing Date:
April 14, 1999
Export Citation:
Assignee:
University of Edinburgh
International Classes:
C12N15/09; C12N5/073; C12N5/079; C12N5/0793; C12N5/0797; C12N5/10; C12Q1/00; C12Q1/04; A61K38/00; (IPC1-7): C12N15/09; C12N5/10; C12N5/06; C12Q1/00; C12Q1/04
Domestic Patent References:
| JPH09500004A | 1997-01-07 | |||
| JPH08322427A | 1996-12-10 |
Foreign References:
| WO1996029395A1 | 1996-09-26 |
Other References:
JPN6010025250, Ｃｉｒｃ．Ｒｅｓ．，１９９６，Ｖｏｌ．７８，Ｎｏ．４，ｐ．５４７−５５２
Attorney, Agent or Firm:
Nobuyuki Kaneda (2 others)