Title:
【発明の名称】シグマ受容体に対して高い結合性を有する置換グアニジンおよびその使用
Document Type and Number:
Japanese Patent JPH05508836
Kind Code:
A
Abstract:
PCT No. PCT/US91/03594 Sec. 371 Date Jan. 22, 1993 Sec. 102(e) Date Jan. 22, 1993 PCT Filed May 22, 1991 PCT Pub. No. WO91/18868 PCT Pub. Date Dec. 12, 1991The invention relates to a method for the treatment or prophylaxis of psychosis, depression, hypertension, or anxiety in an animal by administering an effective amount of an N,N'-disubstituted guanidine or 2-iminoimadazolidine having an affinity for the sigma receptor. The invention also relates to the novel guanidines of the invention as well as pharmaceutical compositions thereof.
Inventors:
Keena, John F W
Webber, Eccard
Webber, Eccard
Application Number:
JP51098491A
Publication Date:
December 09, 1993
Filing Date:
May 22, 1991
Export Citation:
Assignee:
Oregon
International Classes:
A61K31/155; A61K31/00; A61K31/37; A61K31/415; A61K31/55; A61P9/12; A61P25/18; A61P25/20; A61P25/24; A61P25/26; C07B59/00; C07C279/04; C07C279/16; C07C279/18; C07C331/12; C07D233/46; C07D233/50; C07D243/04; C07D311/08; C07D311/14; C07D311/18; G01N33/53; (IPC1-7): C07C279/16; A61K31/155; A61K31/37; A61K31/415; A61K31/55; A61K31/645; C07C279/18; C07D233/46; C07D243/04; C07D311/08; G01N33/53
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)