Title:
【発明の名称】新規な側鎖をもつタキサン類およびその中間体類
Document Type and Number:
Japanese Patent JP3492690
Kind Code:
B2
Abstract:
Novel methods for the preparation of sidechain-bearing taxanes, comprising the preparation of an oxazoline compound, coupling the oxazoline compound with a taxane having a hydroxyl group directly bonded at C-13 thereof to form an oxazoline sidechain-bearing taxane, and opening the oxazoline ring of the oxazoline sidechain-bearing taxane so formed. Novel compounds prepared by the methods of the present invention are also provided.
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Inventors:
Post Michael A
Monioto Jerome El
Trifnovich Ivan Dee
Cousella david jay
Tottatil John Kay
Chen Shu Hui
Way jean mei
Monioto Jerome El
Trifnovich Ivan Dee
Cousella david jay
Tottatil John Kay
Chen Shu Hui
Way jean mei
Application Number:
JP51526694A
Publication Date:
February 03, 2004
Filing Date:
December 15, 1993
Export Citation:
Assignee:
Bristol-Myers Squibb Company
International Classes:
C07C233/17; A61K31/337; A61K31/42; A61P35/00; C07C233/30; C07C233/45; C07C233/82; C07C271/22; C07C309/66; C07C309/73; C07D263/06; C07D263/14; C07D263/16; C07D305/14; C07D307/54; C07D405/12; C07D405/14; C07D407/12; C07D409/12; C07D413/04; C07D413/12; C07D413/14; C07D417/04; C07D417/14; C07F7/18; C07C; C07D; (IPC1-7): C07D305/14; C07D263/16; C07D407/12; C07D413/12; C07F7/18
Other References:
【文献】特許3261548(JP,B2)
Attorney, Agent or Firm:
Minoru Nakamura (6 outside)