Title:
【発明の名称】金属タンパク質分解酵素阻害剤
Document Type and Number:
Japanese Patent JP2001526676
Kind Code:
A
Abstract:
The present invention relates to therapeutically active hydroxamic acid, N-formyl-N-hydroxyamino and carboxylic acid derivatives, their preparation, and pharmaceutical compositions containing them. These compounds are useful in the inhibition of metalloproteases, such as stromelysin, gelatinase, matrilysin, and collagenase. These compounds are useful in the treatment of mammals having disease-states alleviated by the inhibition of such matrix metalloproteases.
Inventors:
Beckett, Raymond, Paul
Martin, fiona, mitchell
Todd, Richard, Simon
Martin, fiona, mitchell
Todd, Richard, Simon
Application Number:
JP55011898A
Publication Date:
December 18, 2001
Filing Date:
May 19, 1998
Export Citation:
Assignee:
British Biotech Pharmaceuticals Limited
International Classes:
A61K31/165; A61P19/02; A61P19/10; A61P35/00; A61P35/04; A61P43/00; C07C233/19; C07C233/22; C07C259/06; C07D233/54; A61K31/197; (IPC1-7): C07C233/19; A61K31/165; A61K31/197; A61P19/02; A61P19/10; A61P35/00; A61P35/04; A61P43/00; C07C233/22; C07C259/06
Attorney, Agent or Firm:
Shintaro Nogawa