Title:
【発明の名称】ジルコニウム中間体から銅中間体へのトランスメタレーション
Document Type and Number:
Japanese Patent JP2883446
Kind Code:
B2
Abstract:
Higher order cuprate complexes are prepared by means of a transmetalation from a corresponding zirconate intermediate. This process is particularly valuable with respect to the preparation of vinylic side chains such as are present in prostaglandins, as it is possible in accordance with the present invention to proceed directly from the acetylenic precursors via the reactive cuprates to the desired final products in a one-pot operation without isolation of intermediates and in high yields. Sequential additions to zirconium intermediates of components which together comprise the cuprate involved in transmetalation with the zirconium intermediate are disclosed as alternative procedures.
Inventors:
RITSUPUSHUTSUTSU BURUUSU HAWAADO
ERUSUWAASU EDOMUNDO RII
ERUSUWAASU EDOMUNDO RII
Application Number:
JP50741791A
Publication Date:
April 19, 1999
Filing Date:
April 01, 1991
Export Citation:
Assignee:
YUNIBAASHITEI OBU KARIFUORUNIA
International Classes:
C07C405/00; C07F1/08; (IPC1-7): C07F1/08
Attorney, Agent or Firm:
Shoichi Hase (2 outside)