Title:
【発明の名称】ヒドロキサム酸に基礎を置くコラゲナーゼ阻害剤
Document Type and Number:
Japanese Patent JP2846737
Kind Code:
B2
Abstract:
Compounds of general formula I: (I) wherein: A represents the group -NH2, a substituted acyclic amine or a heterocyclic base; have collagenase inhibition activity and are useful in the management of disease involving tissue degradation and/or the promotion of wound healing. Diseases involving tissue degradation include arthropathy (particularly rheumatoid arthritis), inflammation, dermatological diseases, bone resorption diseases and tumour invasion.
Inventors:
DEIBITSUDOSON ARAN HOONSUBI
DEITSUKENZU JONASAN FUIRITSUPU
KURIMIN MAIKERU JON
DEITSUKENZU JONASAN FUIRITSUPU
KURIMIN MAIKERU JON
Application Number:
JP50081589A
Publication Date:
January 13, 1999
Filing Date:
November 23, 1989
Export Citation:
Assignee:
BURITEITSUSHU BAIOTEKUNOROJII LTD
International Classes:
A61K31/16; A61K31/165; A61K31/40; A61K31/415; A61K31/4184; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4418; A61K31/445; A61K31/454; A61P17/00; C07D295/12; A61P29/00; A61P35/00; A61P43/00; C07C237/22; C07C259/06; C07C317/44; C07C323/60; C07D207/09; C07D207/335; C07D211/14; C07D213/40; C07D233/60; C07D233/61; C07D235/14; C07D295/13; C07D521/00; C07D207/32; (IPC1-7): C07C259/06; A61K31/16; A61K31/40; A61K31/415; A61K31/44; A61K31/445; C07D207/09; C07D207/335; C07D211/14; C07D213/40; C07D233/61; C07D235/14; C07D295/12
Attorney, Agent or Firm:
Mikio Hatta (2 outside)