Title:
【発明の名称】レチノイドXレセプターに対して選択的な活性を有する化合物、およびレチノイドXレセプターによって媒体されたプロセスの調節手段
Document Type and Number:
Japanese Patent JPH08511027
Kind Code:
A
Abstract:
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, pyrrole, and polyenoic acid derivatives including carbocyclic polyenoic acids. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
Inventors:
Behm, Marcus F
Hayman, Richard A.
The Rin
Fan, Kang Kou
White, steve
Nadzan, alex
Hayman, Richard A.
The Rin
Fan, Kang Kou
White, steve
Nadzan, alex
Application Number:
JP50422395A
Publication Date:
November 19, 1996
Filing Date:
October 22, 1993
Export Citation:
Assignee:
Ligand Pharmaceuticals,Inc.
International Classes:
A61K31/165; A61K31/19; A61K31/336; A61K31/34; A61K31/341; A61K31/35; A61K31/352; A61K31/38; A61K31/381; A61K31/41; A61K31/44; A61K31/4418; A61P3/02; A61P17/00; A61P35/00; A61P35/02; A61P43/00; C07C33/14; C07C47/225; C07C49/242; C07C49/258; C07C49/743; C07C49/757; C07C57/26; C07C57/48; C07C57/50; C07C63/49; C07C63/66; C07C63/74; C07C65/17; C07C65/19; C07C65/34; C07C65/36; C07C65/40; C07C69/608; C07C69/618; C07C69/65; C07C69/76; C07C233/66; C07C233/75; C07C233/81; C07C235/84; C07C309/28; C07C311/21; C07C323/62; C07C325/02; C07C403/20; C07C403/22; C07D213/79; C07D213/80; C07D257/04; C07D303/38; C07D307/68; C07D311/58; C07D333/38; C07D333/40; C07F9/38; (IPC1-7): C07C33/14; A61K31/165; A61K31/19; A61K31/34; A61K31/35; A61K31/38; A61K31/41; A61K31/44; C07C47/225; C07C49/242; C07C49/258; C07C49/743; C07C49/757; C07C57/26; C07C57/48; C07C57/50; C07C63/66; C07C63/74; C07C65/17; C07C65/19; C07C65/34; C07C69/608; C07C69/618; C07C69/65; C07C233/66; C07C233/75; C07C233/81; C07C235/84; C07C309/28; C07C311/21; C07C323/62; C07C325/02; C07C403/20; C07C403/22; C07D213/79; C07D213/80; C07D257/04; C07D303/38; C07D307/68; C07D311/58; C07D333/38; C07D333/40; C07F9/38
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)