Title:
【発明の名称】化合物とその使用
Document Type and Number:
Japanese Patent JP2002539264
Kind Code:
A
Abstract:
4- and 5-oxacyclopent-2-en-1-ones have significant activity in activating HSF and in inhibiting NF- kappa B. They are believed to be useful in treating a wide range of disorders including viral-mediated disorders, bacterial-mediated disorders, disorders mediated by radiation (e.g. by UV-radiation), inflammatory disorders, disorders of the immune system, ischemia, arteriosclerosis, disorders involving cell proliferation (e.g. cancers), disorders involving damage to, or killing of cells (e.g. oxidative cell damage) and diabetes.
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Inventors:
Maria Gabriella Santoro
Stanley Michael Roberts
Thierry Guio
Stanley Michael Roberts
Thierry Guio
Application Number:
JP2000606245A
Publication Date:
November 19, 2002
Filing Date:
March 22, 2000
Export Citation:
Assignee:
Charterhouse Therapeutics Limited
International Classes:
A23K1/18; A23K1/16; A61K31/12; A61K31/5575; A61K31/695; A61P3/10; A61P3/14; A61P9/10; A61P29/00; A61P31/10; A61P31/12; A61P35/00; A61P37/00; A61P39/00; A61P43/00; (IPC1-7): A61K31/5575; A23K1/16; A23K1/18; A61K31/695; A61P3/10; A61P3/14; A61P9/10; A61P29/00; A61P31/10; A61P31/12; A61P35/00; A61P37/00; A61P39/00; A61P43/00
Attorney, Agent or Firm:
Masatake Shiga (7 outside)