Title:
【発明の名称】分解性架橋剤およびこれを用いて形成される架橋網目構造ポリマー
Document Type and Number:
Japanese Patent JP2003503522
Kind Code:
A
Abstract:
Degradable cross-linkers which are used to form polymer networks which degrade under aqueous conditions are described. These cross-linkers comprise a central polyacid, monomeric or oligomeric degradable regions and an optional water soluble regions. These monomers are preferably polymerized using free radical or condensation polymerization. Degradation occurs at the ester linkages after cross-linking polymer filaments, and results in soluble polymer filaments which may be cleared from the body. Preferred applications of these materials include, for example, controlled release of drugs and cosmetics, tissue engineering, wound healing, hazardous waste remediation, metal chelation, swellable devices for absorbing liquids and the prevention of surgical adhesions.
Inventors:
Kaiser, Patrick F.
Thomas, Allen Ay.
Thomas, Allen Ay.
Application Number:
JP2001505600A
Publication Date:
January 28, 2003
Filing Date:
June 22, 2000
Export Citation:
Assignee:
Access Pharmaceuticals, Incorporated
International Classes:
A61K9/16; A61K9/20; C07C219/06; A61L24/00; A61L27/58; A61L31/14; C07C69/675; C07C233/20; C07C243/28; C07D207/46; C08F8/00; C08G63/00; C08G85/00; A61K9/51; (IPC1-7): C08G85/00; C07C219/06
Attorney, Agent or Firm:
Shusaku Yamamoto