Title:
【発明の名称】心血管系の健康用の風味の良いアルギニン化合物およびその使用
Document Type and Number:
Japanese Patent JP2003520846
Kind Code:
A
Abstract:
The present invention is directed to a compound having the structure (I): and acceptable salts, polypeptides, and pro-forms thereof, wherein R is selected from the group consisting of: (a) substituted glycerols; wherein n is an integer from 1 to 2; (b) vitamins; wherein n is 1; (c) sterols; wherein n is 1; (d) stanols; wherein n is 1; and (e) C6-C32 alkyl; and (f) C6-C32 alkenyl; wherein n is 1. The present invention is further directed to compositions and kits comprising these compounds as well as methods of using the compounds. The compounds, compositions, kits, and methods herein are useful for providing general health benefits to the consumer, particularly cardiovascular benefits, anti-menopausal benefits and/or treating sexual dysfunction (particularly, erectile dysfunction). Most particularly, the compounds, compositions, kits, and methods herein are useful for providing cardiovascular benefits, including lowering cholesterol in the consumer, treating, preventing, and/or inhibiting heart disease (e.g., atherosclerosis, restenosis, thrombosis) and, for example, treating other conditions such as hypercholesterolemia, hypertension, poor circulation,and complications associated with diabetes.
Inventors:
Robert Joseph Salama
Raymond Lewis Niehoff
Raymond Lewis Niehoff
Application Number:
JP2001555040A
Publication Date:
July 08, 2003
Filing Date:
January 25, 2001
Export Citation:
Assignee:
THE PROCTER & GAMBLE COMPANY
International Classes:
A23L2/52; A23G1/00; A23G1/30; A23L1/30; A23L1/305; A23L1/308; A61K31/198; A61K31/355; A61K31/575; A61K31/593; A61K47/14; A61K47/44; A61P3/06; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P9/12; C07C279/14; C07C401/00; C07C403/20; C07D311/72; C07J9/00; C07J41/00; (IPC1-7): C07C279/14; A23L1/305; A23L2/52; A61K31/198; A61K31/355; A61K31/575; A61K31/593; A61K47/14; A61K47/44; A61P3/06; A61P3/10; A61P7/02; A61P9/00; A61P9/10; A61P9/12; C07C401/00; C07C403/20; C07D311/72; C07J9/00
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)