Title:
【発明の名称】置換フェニレンジアミン群を含む、複素環式カルボキサミド含有の、ヘルペスウイルスのチオ尿素インヒビター
Document Type and Number:
Japanese Patent JP2002533301
Kind Code:
A
Abstract:
Compounds of formula (I) wherein R1-R5 are independently selected from hydrogen, or substituents R9-R12 are independently hydrogen, or substituents provided that at least one of R9-12 is not hydrogen; G is a monocyclic heteroaryl: X is a bond, -NH, alkyl of 1 to 6 carbon atoms, alkenyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, or thioalkyl of 1 to 6 carbon atoms, alkylamino of 1 to 6 carbon atoms, or (CH)J; J is alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, phenyl or benzyl, useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.
Inventors:
Bloom, Jonathan David
Karan, Kevin J. Joseph
Day Grande, Martin Joseph
Dassin, Russell Giyogi
The Johns, Thomas Lichyard
Lang, Stanley Albert
Ross, Adma Antonia
Telefuenko, Eugene Anthony
O'Hara, Brian Mark
Karan, Kevin J. Joseph
Day Grande, Martin Joseph
Dassin, Russell Giyogi
The Johns, Thomas Lichyard
Lang, Stanley Albert
Ross, Adma Antonia
Telefuenko, Eugene Anthony
O'Hara, Brian Mark
Application Number:
JP2000586708A
Publication Date:
October 08, 2002
Filing Date:
December 06, 1999
Export Citation:
Assignee:
Wyeth
International Classes:
A61K31/341; A61K31/421; A61K31/426; A61K31/433; A61P31/12; C07C335/20; C07C335/22; C07D233/90; C07D263/34; C07D277/56; C07D285/06; C07D307/68; C07D277/20; (IPC1-7): C07D263/34; A61K31/341; A61K31/421; A61K31/426; A61K31/433; A61P31/12; C07C335/20; C07C335/22; C07D277/56; C07D285/06; C07D307/68
Attorney, Agent or Firm:
Heiyoshi Odashima