Title:
【発明の名称】リポ蛋白(a)の血漿濃度を低下させる方法
Document Type and Number:
Japanese Patent JP2001508040
Kind Code:
A
Abstract:
A method of lowering plasma levels of Lp(a) or inhibiting the generation of apo(a) in a human by administering an effective amount of a compound of formula (I): (I) wherein: R1 is hydrogen or alkyl; A, B, D, E, G, R2 and R3 each are hydrogen, and R4 is hydrogen in the beta -position; or R2 with R4, R4 with A, A with R3, B with D, D with E, or G with R2 is a bond, and the other substituents are each hydrogen; or R2 is alkyl in the beta -position and A, B, D, E, G, R3 and R4 are each hydrogen; or R3 is alkoxy in the beta -position and A, B, D, E, G, R2 and R4 are each hydrogen; or R4 is hydrogen in the alpha -position and A, B, D, E, G, R2 and R3 are each hydrogen; and R5 is methyl or ethyl, is disclosed.
More Like This:
Inventors:
Catalin Cowser
Gover Rabney
Gover Rabney
Application Number:
JP51999698A
Publication Date:
June 19, 2001
Filing Date:
October 18, 1997
Export Citation:
Assignee:
Schering Actien Gezel Shaft
International Classes:
A61K31/56; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P43/00; C07J3/00; (IPC1-7): C07J3/00; A61K31/56; A61P3/06; A61P9/00; A61P43/00
Attorney, Agent or Firm:
Toshio Yano (2 outside)