Title:
【発明の名称】プレセニリンとβ-アミロイドペプチドまたはその前駆体との相互作用を阻害し得るペプチド
Document Type and Number:
Japanese Patent JP2001521043
Kind Code:
A
Abstract:
The invention concerns novel peptide and nucleotide sequences, and their pharmaceutical use. More particularly, the invention concerns novel polypeptides capable of inhibiting at least partially the interaction between presenilin 1 or presenilin 2 and the beta -amyloid peptide precursor and/or the beta -amyloid peptide. The invention also concerns the preparation of in vitro tests for detecting molecules and in particular molecules capable of inhibiting said interaction.
Inventors:
Chiesyu, Kristian
Marken, Liyusk
Pradeie, Loran
Le Bourg-Bekar, Soline
Marken, Liyusk
Pradeie, Loran
Le Bourg-Bekar, Soline
Application Number:
JP2000517994A
Publication Date:
November 06, 2001
Filing Date:
October 23, 1998
Export Citation:
Assignee:
Avantes Furuma S.A.
International Classes:
A61K38/00; A61K38/16; A61K39/395; A61P25/28; C07K14/47; C07K16/18; C12N1/21; C12N5/10; C12N7/00; C12N15/09; C12N15/12; C12N15/86; C12P21/02; C12Q1/68; G01N33/50; G01N33/542; G01N33/566; G01N33/68; A61K48/00; (IPC1-7): C07K14/47; A61K38/00; A61K39/395; A61P25/28; C07K16/18; C12N1/21; C12N5/10; C12N7/00; C12N15/09; C12P21/02; C12Q1/68; G01N33/50; G01N33/566
Attorney, Agent or Firm:
Yoshio Kawaguchi (3 outside)