Title:
【発明の名称】ニューロキニンアンタゴニストとしてのピペラジノ誘導体
Document Type and Number:
Japanese Patent JP3447745
Kind Code:
B2
Abstract:
The invention relates to compounds of formula (I) wherein Z, Rc, y, m, u, Ar2, n, X, Rc',(I) and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.
Inventors:
Shu, Ho Jen
Si, Nen-Yang
Blysin, David Jay.
Chen, Zao
Piwinski, John Jay.
McCormick, Kevin Dee.
Si, Nen-Yang
Blysin, David Jay.
Chen, Zao
Piwinski, John Jay.
McCormick, Kevin Dee.
Application Number:
JP51006997A
Publication Date:
September 16, 2003
Filing Date:
August 29, 1996
Export Citation:
Assignee:
Schering Corporation
International Classes:
A61K31/40; A61K31/439; A61K31/445; A61K31/46; A61K31/495; A61K31/496; A61K31/497; A61K31/498; A61K31/4995; A61K31/50; A61K31/501; A61K31/505; A61P1/00; A61P9/00; A61P11/00; A61P11/06; A61P11/14; A61P13/02; A61P15/00; C07D487/08; A61P25/00; A61P25/04; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P29/00; A61P37/00; A61P37/02; A61P37/08; A61P43/00; C07D241/04; C07D401/06; C07D401/12; C07D401/14; C07D403/12; C07D405/12; C07D405/14; C07D409/14; C07D413/14; C07D417/14; C07D453/02; C07D453/06; C07D471/08; C07D487/04; C07D487/18; (IPC1-7): C07D401/12; A61K31/496; A61K31/497; A61K31/498; A61K31/4995; A61K31/50; A61P1/00; A61P9/00; A61P11/06; A61P25/00; A61P27/02; A61P29/00; A61P37/06; A61P37/08; C07D401/14; C07D405/14; C07D409/14; C07D451/04; C07D487/18
Attorney, Agent or Firm:
Shusaku Yamamoto